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Lewis Drug

About Us

Your first stop for over 75 years.

Since 1942, shoppers have trusted family-owned Lewis as their neighborhood store and pharmacy. With 45 stores conveniently located throughout South Dakota, Iowa and Minnesota!

In addition to quality prescription and non-prescription drugs, Lewis has a huge selection of everyday basics, plus name brands and specialty items—always at affordable prices.

You’ll find everything on your list along with a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

At Lewis, we promise you’ll be greeted with exceptional prices, friendly service and great products every time you walk through our doors. Make Lewis your first stop for all your family’s needs.


  • Medical
  • Dental
  • Vision
  • 401k
  • PTO
  • Flexible Spending Accounts
  • Short Term Disability
  • Long Term Disability
  • Company Paid Life Insurance
  • Voluntary Life Insurance
  • Group Cancer Plan
  • Group Accident Plan
  • EAP

Jobs at Lewis Drug

Sioux Falls, SD

Are you a people person? Part time cashier positions are available at Lewis Drug locations throughou

The DC Associate is responsible for receiving, storing and distributing products within the Distribu

Spring is just around the corner! Lewis Drug is now accepting applications for garden season. Garden

Brandon, SD

SUMMARYOperates cash register to itemize and total customer’s purchases in grocery, department

Department Manager

Lewis Drug

Sioux Falls, SD

The Department Manager works with the Store Merchandise Manager in the task of replenishing merchand

Dell Rapids, SD

Summary Assist Pharmacist in duties of dispensing medication to patients that are within the scope

Sioux Falls, SD

Summary: The primary responsibility of the pharmacy technician is customer care.  Customer ser

Dell Rapids, SD

The pharmacy clerk’s primary responsibility is customer service.  Being aware of all cust

The pharmacy clerk’s primary responsibility is customer service.  Being aware of all cust

Lewis Drug logo

Contact Info

  • 2701 S. Minnesota Ave.
    Suite 1
  • Sioux Falls, SD 57105